Smoking daily 2 years5/5/2023 After restricting to people 40–79 years old who smoked ≤40 cigarettes per day at enrollment, we fit Poisson models for four age groups and evaluated lung cancer mortality ( M) in relation to smoking duration ( D) and intensity ( I) on a double-log scale, as suggested by the Armitage-Doll multistage carcinogenesis model. We studied participants in the Cancer Prevention Study II, followed from 1982 through 1988. The separate contributions of smoking duration and intensity to lung cancer risk have not been evaluated in other large prospective studies. Their findings have been interpreted to mean that smoking duration is much more important than smoking intensity in causing lung cancer. Health, 32: 303–313, 1978) in their historic analysis of one of the few large cohort studies in which intensity and duration were estimated separately. The magnitude of the effect of smoking duration on lung cancer mortality relative to that of intensity (cigarettes/day) has practical implications for both tobacco control policy and research.
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